Respiratory-tract infections; otitis media; skin and soft-tissue infections; uncomplicated genital chlamydial infections and non-gonococcal urethritis; mild or moderate typhoid due to multiple-antibacterial-resistant organisms; prophylaxis of endocarditis in children.
Dosage & Administration
- 500 mg once daily for 3 days; Child over 6 months, 10 mg/kg once daily for 3 days; or body-weight 15-25 kg, 200 mg once daily for 3 days; body-weight 26-35 kg, 300 mg once daily for 3 days; body-weight 36-45 kg, 400 mg once daily for 3 days.
- Uncomplicated genital chlamydial infections and non-gonococcal urethritis, 1 g as a single dose.
- Typhoid, 500 mg once daily for 7 days.
Direction for Reconstitution
Shake the large bottle well before adding diluent. The small bottle contains the diluent; the large bottle contains the powder. Pour the diluent (from small bottle) completely into the large bottle of powder. Do not add water to the suspension. Close the bottle tightly & shake vigorously until it is properly mixed. The suspension is ready for use. Shake the bottle well before each use.
Rare serious allergic reactions, including angioedema and anaphylaxis, have been reported. It is important to consider this diagnosis in patients who develop diarrhoea or colitis in association with antibiotic use (this may occur up to several weeks after cessation of antibiotic therapy). The use of Azithromycin should be undertaken with caution in patients with significant hepatic disease. Azithromycin should be used with caution in patients predisposed to QT interval prolongation or in patients taking other medications known to prolong the QT interval. However, because of the theoretical possibility of ergotism, Azithromycin and ergot derivatives should not be co-administered. As with any antibiotic preparation, observation for signs of superinfection with non-suspectible organisms, including fungi is recommended. Pregnancy and lactation: Safety for use in human pregnancy and lactation has not been established. Azithromycin should be used in pregnant or lactating women only where adequate alternatives are not available.