Indication

It is a topical eye antiviral that is indicated for the treatment of acute herpetic keratitis (dendritic ulcers).


Dosage & Administration

The recommended dosing regimen for Ganciclovir eye gel 0.15% is 1 drop in the affected eye 5 times per day
(approximately every 3 hours while awake) until the corneal ulcer heals and then 1 drop 3 times per day for 7 days.


Precautions

It is indicated for topical eye use only. Patients should not wear contact lenses if they have signs or symptoms of herpetic keratitis or during the course of therapy with it.

Use in special population
Pregnancy
Pregnancy Category C. Ganciclovir has been shown to be embryo toxic in rabbits and mice following intravenous administration and teratogenic in rabbits. Fetal resorptions were present in at least 85% of rabbits and mice administered 60 mg/kg/day and 108 mg/kg/day (approximately 10,000x and 17,000x the human ocular dose of 6.25 mcg/kg/day), respectively, assuming complete absorption.
Nursing Mothers
It is not known whether topical eye ganciclovir administration could result in sufficient systemic absorption to produce detectable quantities in breast milk. Caution should be exercised when it is administered to nursing mothers.
Pediatric Use
Safety and efficacy in pediatric patients below the age of 2 years have not been established.
Geriatric Use
No overall differences in safety or effectiveness have been observed between elderly and younger patients.


Product Details


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