Nitroglycerin is used for the prophylaxis and long term management of angina pectoris, heart failure and myocardial infarction.
Dosage & Administration
The dosage is determined on the basis of individual requirement depending on the severity of the disease, response to Nitroglycerol and development of side effects. The usual daily dose is initially 1 tablet twice daily. The dose may be gradually increased to 2-3 tablets twice daily.
Nitroglyceri n should not be used in patients with severe hypotension , hypovolemia , marked anemia, heart failure due to obstructio n (including constrictive pericarditis), or raised intracranial pressure due to head trauma or cerebral hemorrhage. It should be used with caution in patients with severely impaired renal or hepatic function, hypothyroidism, malnutrition, or hypothermia. Use in Children: Safety and efficacy for use in infants and children have not been established. Use in Pregnancy: Safety for use during pregnancy has not been established. Use only when clearly needed and when the potential benefits outweigh the unknown potential hazards to the fetus. Use in Lactation: Safety and efficacy for use in nursing mother has not been established.