BenozolTM is indicated in the treatment of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma.

Dosage & Administration

Shake well before use.
Insert 1 drop in the affected eye(s) three times daily. It may be used concomitantly with other topical ophthalmic products to lower intraocular pressure. If more than one topical ophthalmic drug is being used, the drugs should be administered at least ten minutes apart.


Brinzolamide is a sulfonamide and although administered topically it is absorbed systemically. Therefore, the same types of adverse reactions that a re attributable to sulfonamides may occur with topica l administration of Brinzolamide. Fatalities have occurred, although rarely, due to severe reactions to sulfonamides including Stevens-Johnson syndrome, toxic epidermal necrolysis, fulminant hepatic necrosis, agranulocytosis, aplastic anemia, and other blood dyscrasias. Sensitization may occur when a sulfonamide is re-administered irrespective of the route of administration. If signs of serious reactions or hypersensitivity occur, discontinue the use of this preparation. Because Brinzolamide and its metabolite are excreted predominantly by the kidney, Brinzolamide is not recommended in renal impairment patients. Brinzolamide- has not been studied in patients with hepatic impairment and should be used with caution in such patients.


Use in Pregnancy & Lactation:

Pregnancy Category C.
There are no adequate and well-controlled studies in pregnant women. It should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
Nursing Mothers:
It should be used only if the potential benefit justifies the potential risk to the baby.
Pediatric Use:
One drop in the affected eye(s) 2 times daily in pediatric patient (4 weeks to 5 years age)
Geriatric Use:
No overall differences in safety or effectiveness have been observed between elderly and younger patients.

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