Indication
Brimopres sterile eye drops is indicated for the reduction of elevated intraocular pressure (IOP) in patients with glaucoma or ocular hypertension who are insufficiently responsive to topical beta-blockers.
Dosage & Administration
The recommended dose is one drop to the affected eye(s) twice daily. In order to minimize systemic absorption, apply pressure to the tear duct immediately following administration of the drug.
Precautions
Like other topically applied ophthalmic agents, it may be absorbed systemically. No enhancement of the systemic absorption of the individual active substances has been observed. Due to the beta-adrenergic component Timolol, the same types of cardiovascular and pulmonary adverse reactions as seen with systemic beta-blockers may occur. Caution should be exercised in treating patients with severe or unstable and uncontrolled cardiovascular disease.
There is no adequate data on the use of this preparation in pregnant women. Timolol is excreted in human milk and there is potential for serious adverse reactions from Timolol in breastfed infants. Therefore, a decision should be made whether to discontinue breast feeding or to discontinue this eye drops, taking into account the importance of this eye drops to the mother.
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