Naspro is indicated for the treatment of rheumatoid arthritis, osteoarthritis (degenerative arthritis), ankylosing spondylitis, juvenile rheumatoid arthritis, acute gout, and acute musculoskeletal disorders (such as sprains and strains, direct trauma, lumbosacral pain, cervical spondylitis, tenosynovitis and fibrositis) and dysmenorrhea.

Dosage & Administration

Adult: Rheumatoid arthritis, osteoarthritis and ankylosing spondylitis: the usual dose is 500 mg to 1 g daily taken at 12-hour intervals or alternatively as a single administration of two tablets morning or evening.


Acute gout: 750 mg initially, then 250 mg every eight hours until the attack has passed.


Acute musculoskeletal disorders: 500 mg initially followed by 250 mg at 6-8 hour intervals as needed to a maximum 1250 mg daily.


Children: Naproxen is effective in the treatment of juvenile rheumatoid arthritis in children over five years of age at a dose of 10 mg/kg day taken in two doses at 12-hour intervals.


Naproxen should be given under close supervision to patients with a history of gastrointestinal disease. Bronchospasm may be precipitated in patients suffering from, or with history of bronchial asthma or allergic disease. As Naproxen is eliminated to a large extent (95%) by urinary excretion via glomerular filtration, it should be used with great caution in patients with impaired renal function and the monitoring of serum creatinine clearance is advised in these patients. Naproxen is not recommended in patients having baseline creatinine clearance less than 20 ml/minute. Use in pregnancy and lactation: Naproxen affects the human fetal
cardiovascular system (closure of the ductus arteriosus), and use of this class of therapeutic agent requires cautious balancing of possible benefit against potential risk to the mother and fetus especially in the first and third trimesters. Naproxen has been found in the milk of lactating mothers. The use of Naproxen should therefore be avoided in patients who are breast-feeding.

Product Details

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