Indication

Candicon is indicated in adults and children aged 2 years and above as follows:
• Treatment of invasive aspergillosis
• Candidemia in non-neutropenics and other deep tissue Candida infections
• Treatment of fluconazole-resistant serious invasive Candida infections
• Esophageal candidiasis
• Treatment of serious fungal infections caused by Scedosporium spp. and Fusarium spp.


Dosage & Administration

Candicon is to be taken at least one hour before or one hour following a meal. For Patients 40 kg or above: Loading Dose: 400 mg twice daily (for the first 24 hours) Maintenance Dose: 200 mg twice daily (from the 2nd day) For Patients less than 40 kg: Loading Dose: 200 mg twice daily (for the first 24 hours) Maintenance Dose: 100 mg or 150 mg twice daily (from the 2nd day) Route of Administration: Can be taken orally. Use in Special Populations Elderly: No dose adjustment is necessary for elderly patients. Renal Impairment: No adjustment is necessary for oral dosing for patients with mild to severe renal impairment. Hepatic Impairment: Use half of the maintenance dose in patients with mild to moderate hepatic Impairment.


Precautions

Pregnancy and Lactation
Voriconazole can cause fetal harm when administered to a
pregnant woman. It is not known whether Voriconazole is excreted
in the milk of laboratory animals or in human breast milk.
Voriconazole must not be used in nursing mothers unless the
benefit clearly outweighs the risk.
Pediatric Use
Safety and effectiveness in pediatric patients below the age of 2
years has not been established. Therefore, Voriconazole is not
recommended for pediatric patients less than 2 years of age.


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